I tried it with a Nuvi 360 but the various mounts I tried didn't seem like they would hold over some of the stiffer bumps. The lack of waterproofing is also a problem as someone mentioned, as is daylight (and night visibility). In the end I sold the Nuvi and got a 705. $323 and that includes HR strap and cadence sensor, plus two bike mounts so it doesn't end up being that much more expensive than a car GPS. The 705 GPS is also a lot more sensitive than the 360 was, so more likely to be able to hold signal in an enclosed or hilly area.