use this gear calculator
www.sheldonbrown.com/gears to tell you that it won't make much difference at all.
example: 700c x 25 wheels, 165mm cranks, 48-16 gearing gives you 79.1 gear inches. 46-16 will give you 75.8 gear inches.
If you want to go faster after getting the Pake crankset, get a 15T cog. That would give you a 46-15 with 80.9 gear inches.