I'm curious about the OP's question too. I have small hands and Tiagra shifters and have some trouble. I use shims to bring the levers closer to the handlebars, but the throw is still a problem. Basically I can't shift to the big ring in front while riding in the drops without involving a lot of elbow movement and moving my hand around in a fashion that I'm not comfortable with, and is certainly not optimal. Rear shifting is fine since I got the shims, there's a lot less movement required compared to the front.

This isn't a huge problem because the small chain ring (34) often correlates to riding on hoods, but I'd still be interested in fixing it some day, either with 105/ultegra if those are different, or even a shimergo set up since I've heard campy shifters fit small hands better, although I'd like more specifics on what that means as well.