It's going to be all MTB components in the rear right? You should be fine. You can usually mix road and MTB parts in the rear as long as you stay within the limits of the derailleur as far as max cog size goes and use the proper cage length.

Front dérailleurs are road or MTB specific with Shimano. You can't mix road shifters with MTB derailleurs. Derailleurs are also optimized for certain ring sizes and are designed specifically for doubles or triples. If your current derailleur was intended for a max ring size of 42, it may not work so good with a 52.