I've had good results with the 23 and 25mm versions on my road bike and on various commuting cross/hybrids/fixies. Not too many problems with flats, although certain items (staples, nails) are going to go through almost anything. Tread wear has been very good. The tires feel a bit heavier than I prefer on the road bike, but more rugged IMO than the lighter tires. I have had some problems mounting them when new, although the beads seem to soften/loosen enough that when I have needed to fix a flat, it hasn't been too much of a hassle. I know a number of roadies who use the gatorskins as their winter training tire and have been happy with their results.