My 48T ring is getting close to death. Cheap ring--6061 AL--and the chain is gouging the teeth pretty bad. I decided to get a new ring (7075 AL) before it dies, but I couldn't find a 48T or 49T to replace it. I bit the bullet and ordered a 50T, so my gear inches will go up to 82.4.
50x16 in a hill city, but you only live once. If my knees don't assplode, I guess it'll only make me stronger.