The very first step in getting good fit is positioning the saddle correctly, both for height and for forward/back with respect to the pedals. When you're turning the pedals effectively, with good extension and no hip movement, and feel comfortable with your power position, then it's time to position the handlebars, not before since any repositioning of the saddle would negate whatever you do to the bars.

My first response was purely from the mechanical considerations, but for fit remember that you'll never get anywhere unless you know where you're going. Figure out what you want, or get a pro to help you, then make the necessary adjustments.