As you go from 700c to 26, and then move into big frames, thing can start to look "odd" indeed.
A Rodriguez touring bike in 700c:
Same bike w/26-inch wheels; appears to be a bit bigger:
Now even larger frame, w/26-inch wheels:
They make very nice bikes, by the way -- I also chat w/their owners when I see them and invariably they have good things to say.