I know that ultimately the angle of the seat is going to vary according to personal preferences - still, what "most" people do can serve as a good starting point in the process.

So, on a road bike, do you try to have your saddle exactly parallel to the ground or titled up or down to some degree? I'm still trying different things with mine. I found that a slight tilt up didn't seem to work for me. I just got a new saddle and that could make a difference, I guess, but I haven't had time to check.