Originally Posted by roccobike

This response will be similar to the last time I responded to this question. I'm not aware of any CF frames from major brands that have acquired a reputation for failure that would injure the rider. Trek has had problems with bottom bracket housing coming loose thus rendering the frame useless. I understand this is more common on their MTBs. But if you are the original owner, they will replace the frame. As for other materials, bonded frames from the 80's had their share of problems and it's still not advisable to spread the 126mm dropouts to 130 to upgrade one of those frames.
The only other frame material where I know there have been major failures after long periods of time is steel. There are a number of threads over on the C&V about someone's steel frame giving up due to rust after 20 or 30 years and thousands of miles of service. I've never had this happen to me and my Nishiki Ariel MTB is still in service, still taking a pounding over non-paved trails. Of course you can prevent many steel frame failures by using frame saver.