+1 on the Ergon Grips, (bar-ends help too, multiple hand positions). Pulled the trigger on some recently much MUCH better. I believe AdamDZ and I have the same ones:
http://www.amazon.com/Ergon-Race-Bic...ef=pd_sbs_sg_8 a bit "spendy" but.......
Obviously this is in tandem with better positioning on the bike as has been suggested.