I test rode Cervelos for almost 4 hours yesterday. It was exhausting, but well worth the time and effort.
I rode: S2 with Ultegra, S3 with DA twice (web managers bike with SRM, which was cool), S3 with Red, and a R3-SL with Di2. Tried Zipp 303s, 404s, DA carbon tubies, and some new DT tubies on the web manager's bike.
Di2 was buttery smooth, but I'll happily pay half and ride Record. SRAM is junk, although one of the SRAM designers was there and tried to convince me otherwise. He said it takes "a lot of getting used to," which is the nice way of saying it sucks. The new Shimano hoods are a vast improvement. And the R3-SL is a stiff, yet plush ride.