I've been using FiveFingers too, and love them. I never ran much in running shoes, so can't really compare the two. I used to use the fivefingers on the bike for casual and training rides. Ventilation seemed to be the nice feature of fivefingers on the bike. I decided clipless was a better choice for me, though. With the right shoe, you can get almost the same ventilation, and I like the other advantages of clipless.