So, just tried my 2nd seat bag...a Louis Garneau Little Stream.
Same problem, though not as pronounced as it was with the Topeak Aero Wedge (L).

I think it's official.

My thighs are too large for a seat bag that ties into the seat post.
So, I'm going to have to wait until I get a Fizik Aliante and a Fizik ICS Saddle Pak.

I'm 5'9" @ about 210lbs. Measurements are 44/34/42.
No matter how much I'd drop in my waist (I'm working to get back to a 180-190lb range),
I'm always going to have very big thighs (muscle...from 25+ years of Roofing).

I'm even considering designing my own bag and having my GF sew it together for me with some type of quick-connect system that'll just attach to the rails and hold the bag/pack far back from the post (but it'll have to also be aesthetically pleasing and will have to look like it belongs right where it is).

I think it's going to be a couple of months before I spring for a Fizik Saddle.
I have other things I'd rather spend my money on first (wheelset, tires, etc...).

I'm just wondering if there are any other riders at around my size or who just have
big thighs that can't ride with seat bags that attach to their post and are using some
other type seat bag?

Suggestions?