Short answer Yes. Long answer kinda, you need hands to be pretty strong. My palm by the thumb also ends up hurting and it takes a while. Some of it depends on the tire and the wheel as well as the all important how long the tire has been installed. I find a fresh wheel from the package hard to install, but once the tire has been on for 6+ months it is much easier to put on and off. The worse set was a pair of Armadillos that I left partially on the wheel with the tube inflated to stretch it out some so I could get it on the next day, that was with tire levers are home, with cursing. I find cursing helps.