Several frames are now made this way. Both the Surly Karate Monkey and Soma Juice have derailleur hangers and track style fork ends but this is for versatility so they can be built as derailleur, single speed or IGH configuration bikes.

IMO the derailleur spring is not strong enough to have much effect on wheel retention and almost all high end bikes of the era used semi horizontasl front opening dropouts which allowed fitting adjustable wheel stops. These allowed more rapid wheel changes with proper wheel alignment.