During my commutes, yes... I wear a high vis vest and have orange shirts that I wear. In the image below, you can see my typical commute "fred" look.
Since this pic was taken, I have a new helmet and new panniers... but I still wear this clothing.
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I am thinking of a new paint job for the bike... and want to add some reflective patches to the bike and get a much more reflective vest. My route is is on 45 MPH and 50MPH arterial roads and a small section of interstate 5.