I too have gone through my fair share of saddles. I recently cracked my much loved SLR saddle (a freak occurence I think - the US distributor for Selle Italia will heopfully replace it under warranty - on its way now...) and have reverted to my Flite which is killing me.

Admittedly the first week I had the SLR I just about died but after that, oh my, its the best saddle I have ever used. So minimal and doesn't get in the way of my thighs, or clothes or whatever. It's just there.

I bought a Selle San Marco Aspide Arrowhead (can we make saddle names any longer?) over the weekend and did a 75 mile ride - it was horrible. I returned it the next day.

Your mileage may vary definitely with saddles. It seems I like the minimal padding, flat saddles the best rather than rounded padded ones.

I'm surprised no one has chimed in yet with the Brooks recommendation.