No - you either need skinnier tires or wider fenders and/or front mud flaps.
Most stock mud flaps on fenders are ridiculously too small and seem to be designed by people who have NEVER ridden in the rain - one exception being the PB cascadia fenders with the long flaps that actually work pretty well. I ride a LHT with 35mm tires and fenders rated to a 42mm tire...but are actually better for tires at 35 or smaller to be honest.
If your tire is nearly as wide as the fenders are rated for (which they over-rate also) you'll also get some water on you as well.
I've also made my own flaps by cutting stair tread (home depot) and using little bits of hardware and it works great.