To reduce the preponderance of doping in the pro peloton... put pressure on the sponsors.
It would be interesting to see just how fast corporate sponsorship would dry up if an anti-doping bond were required... say $2-5 million annually, in that if any of 25 riders on a ProTour team received an adverse analytical finding, the team would forefit their bond on deposit with the UCI (or third party escrow).
I firmly believe that there are a host of drugs out there already which no one really knows about publicly yet, are untestable at the moment, and are in widespread use.