I "rear ended" one of the big black bumble bees a few years ago in my lip. Instant pain and swelling. Same area a year ago, took a yellow jacket to the forehead at 40+ miles an hour.
I always carry a couple benadryl capsules in my seat pack. Real easy to break it open, mix the powder with a little water and put it on the sting. Cuts the swelling and the pain in a matter of minutes.
Jerry