I haul everything in a large messenger bag. My bike handles better, performs better in the wind, and my upper body core muscles get a mild workout.
I'll even stop in on my way home on Friday and throw 12 longnecks and a bottle of wine in there in addition to clothes and papers for work.
My commute ranges from 10 to 33 miles r/t. I have not ridden with a back pack, but I imagine that it would sway a lot in addition to the sweat factor.
The panniers stay on my old hybrid set up for shopping.
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The bicycle, the bicycle surely, should always be the vehicle of novelists and poets. Christopher Morley