We've tried it all and came back to the plain ol' blue closed cell pads... Although I really like the comfort of the inflatables, they are too unreliable for a long tour. When you are passing through very cold temps and absolutely HAVE to have the insulation from the ground, it's not worth risking a puncture in the inflatable - your life could literally depend on it.

While our closed cell pads are bulky (and we need to carry four of them!), they don't weigh anything. We just strap them on top of our BOBs and are good to go.