Greer has typical suburban traffic, so I don't really consider it to be the best area for cycling. The residential areas just north of downtown Greenville are much more bike friendly. George Hincapie lives in Montebello, which would be a great place to live and ride if you can afford it. There are quite a few cyclists in the North Main neighborhood as well. I can't speak for Simpsonville, and the suburbs south of town, but I do know that quite a few cyclists live in those areas as well.