I was running a double record crank w/ a 105 triple shifter and a 105 triple fd. the limiting screws are the key. The shifter takes like 3 or 4 clicks to move onto the big ring but thats ok because then you can trim for all rear positions.
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2010 Kestrel RT900SL, 800k carbon, chorus/record, speedplay, zonda
2000 litespeed Unicoi Ti, XTR,XT, Campy crank, time atac, carbon forks