Have to set up a real OCD test facility to tell any aero difference between head in and head out , how small a fraction of time/distance change will be significant?

FWIW
Brompton's Front wheels are laced radial , heads out , to fit in the fork,
only 75mm wide.
except when theres a dyno-hub put in there, those cross.

Flange is larger diameter too , so further from the dropout.