In all my years of touring, the only times that I have paid heed to headwinds or tailwinds is when they have been strong enough to significantly affect my progress. Which happens only occasionally.
I am not convinced that prevailing winds have much effect at ground level in the presence of trees, forests, rivers, lakes, rock faces, hills, buildings, and so on. Besides, even when trying to go from Point A to Point B in the most direct way possible, there are usually twists and turns, detours, side roads, and so on.