I use Carradice Super C at the back and Ortleibs at the front. I use drybags inside the carradice because they are a bit old and worn in places but they are good for storing damp clothing without getting mildew.
Ortleibs are good for food. Ive had a (pesto) oil leakage inside one pannier and could wash the material clean and dry it easily. I can leave the Ortleibs outside my tent during the heaviest rain without worrying.

The weight of a pannier is mostly due to the stiffening material. Heavy board or metal is no better than the lightweight corrugated plastic of the Carradice.
I'm not a fan of zippers, compartments or pannier covers.
Heavier grade fabric is more durable and flaps around less.
Ive tried cheap, thin, heavy panniers and prefer the better ones.