I have a 58cm '07 Fuji Roubaix RC (I believe the ACR 1.0 replaced it) and it is a great bike. I'm 6' and around 230 lbs. It is a light and comfortable ride. The carbon stays make a noticeable difference in comfort (I actually thought my back tire was going flat the first few rides). Never been concerned about durability and I hit potholes, RR tracks and other stuff regularly. Don't see why a larger frame would be any diferent.
My wife has an '06 Fuji Finest 1.0 which is the women's version and loves hers as well.