You might want to ooch the cleats forward, say 1/4" at a time, and try them for a few days. Then you can move them again, or stop if they're comfortable.
I don't think it makes much sense to vary releast tension from side to side. You're having to train your brain and legs to swing out, why make it harder by having one leg tighter than the other? Also, it makes sense to put the left fot down, since it doesn't have to reach as far on crowned roads.
If your knee starts to hurt, stop quickly and figure out which way you need to angle the cleat. If you're good or lucky, you'll not need this tip.