I wouldn't really call it a "neighborhood", but there is an open area near the end of my commute where the homeless tend to camp. In the morning they trek on the bike path over to the soup kitchen.

Every once in a while there is a news report of crime in this area. When I first started commuting on this route I was a little worried about cycling through here. In the year I've been using this route never had any problems. I just pedal on through.