Oh man! Change them NOW! I put somewhere around 5000 miles on my CAAD9's stock RS10s. They went out of true only one time and that was when I hit a massive pothole going downhill at around 30mph. The problem is I had no idea how bad they were.

I replaced them with a set of Williams System 30s. WHOA!!!! Changed my whole bike. The hubs roll smoother, my whole bike is smooth - the vibrations have completely stopped and I can ride for four hours comfortably - and that's on an aluminum race frame!

I was going to buy a carbon bike and still may in the future but for now getting rid of those RS10s has made all the difference. I can't implore you to do it enough. It's seriously like riding on concrete or wooden rims.

DO IT!