Zipp 101s and Zipps 303/Reynold Assaults serve two different purposes. 101's are the latest in wider rims. They will handle and corner batter. They also are fairly lightweight so that helps with climb. Zip 303s/Reynold Assaults are aero and probably weigh close to the stock wheels. But they will make you faster on the flats and rolling hills.

The bottim line is it worth $2000 - $2700 for that kind of improvement? With me, I train fairly hard, don't have excess weight, and had the money so I got 303's. I really like them. I've had them for five years and they have been trouble-free.