There's an interesting article about a guy who has one-way 50 mile commute (come caveats, he does it twice a week, breaks up ride but still a good read for commuters)
Article here http://outsideonline.com/adventure/t...ev_154507.html

To answer the OP, I definitely think it's doable but sure is a lot of miles (12k a year or so?!?). I'd make sure to have the standard commuter equipment (2-3 spare tubes, lights, fenders, clothing/gear) and some.