Col. Those are 26 x 2.25" and the tight spots are at the front fork blades and at the chainstays. Its tight, i certainly couldn't go any bigger.
When I initially started building this bike I had Fat Franks in mind, but they won't fit. Maybe with a Narrower rim you'd have a shot but I'd be skeptical.
weight savings is not a concern. Just lookin good and possibly adding a little range for hill climbing. the Derailleurs can handle it.
No need to describe the process, I know how it goes
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--Don't Panic.