I'll take a day off if I'm feeling extremely sick, but that is rare. Or I might drive in if I plan on running some errands that require the car (this is about once a month now). I'm not car-free by any means, but it's not really difficult to ride every day of the week. Even if I don't get much sleep and feel a little out of it I perk up once I'm on the bike, and by the time I get to work and hit the shower I'm feeling great. Some days my legs are really tired and I feel a severe lack of energy especially in the afternoon, but I use it as an excuse to take it extra easy and I still end up enjoying the ride. Headwind of course totally sucks, but every other part about weather makes if fun. I live in Texas and wish it would rain here more often.