Back in the 80s we tested some new tires for Avocet.
Blew both of them in one week.
First, the front blew off the rim.
Second, rear tire blew off the rim and wrapped the tube into freewheel of our tandem creating an instant panic stop.. The guy drafting us got showered by tube debris.
Neither event caused us to crash but did create some excitement!
Believe lousy wire beads were at fault.
Rims were Mavic MA40s; butyl tubes. Other tires never blew off those rims.