Is there existing space available to unload these trucks? Or would this be a requirement for future stores? I doubt that 1 square foot of NY real estate would be used for a loading dock unless absolutely necessary. And are trucks able to get to these locations without travelling on residential streets? I know we have strictly enforced weight limits here.

As far as smaller trucks, from a purely financial view, I can't see that happening. We move about 1,300 metric tonnes of aluminium per day, all by rail. We bring in our empty containers by rail as often as possible too. Next choice is 3 containers on a B Double. Our most expensive option is one box on a single truck. The difference between rail and trucks works out to $50/container x 300 containers/week. A single truck can deliver to multiple locations in one day. A smaller truck may have to go in and out of the city several times to deliver goods, or the supplier needs to send out more trucks to achieve the same volume. That means more truck miles for the same quantity of goods. Two prime movers put out twice as much pollution as one, and probably use twice the fuel, given that so much time is spent idling in traffic. To sum it all up, unless consumers will accept higher prices for their goods, the bigger trucks are going to have to be in city, and cyclists, pedestrians and motorists will need to deal with that.