I have 28mm Ultra Gatorskins with slime tubes on my faster bike. It seems to work pretty well for me in Chandler, Az. I do notice that I sometimes see my tires crying little slime teardrops (note I said tire -- this is on the outside!). I don't like the weight, but I hate flats. I'm afraid to take off my tires to see what the tubes look like.

What I hate most is that I seem to be pretty incompetent at patching tubes. Patches pretty much never seem to work right for me.