Originally Posted by
Eightydeuce
One thing I did like about the Trek I test rode was the hand grips had some extra support under the "meat" of my palms, that was nice. I'm guessing other brands have something similar or at least I could put something aftermarket on?
Yep. These grips are an easy add-on if the bike you choose does not have them. By no means should their absence be a deal killer on a bike you otherwise love.
Ergon makes excellent quality ergonomic grips ranging from $20-$50 depending on model. There are other brands, too (Portland Design Works "Dapper Dan", etc), plus cheap slide-ons (not recommended).
For saddle, bear in mind that there will be a physiological adjustment period on ANY saddle, which includes some soreness as your butt adjusts to the new pressure points. Most competent shops can help guide you on saddle choice depending on your own sit bone spacing. I highly recommend a saddle with a "cutout" or channel to alleviate pressure in the perineum, or a traditional leather saddle (such as Brooks B-17).