One of the bikes I use for a 44 mi RT commute is a tadpole (Catrike Road). The biggest issue I encounter is that trikes take so much space that unless you have a wide shoulder to ride on if there is a significant speed disparity between you and the cars, it can get dicey. Also, with three wheel tracks to hit debris rather than one, you can get destabilized if the roads aren't somewhat clean. Generally speaking, I like to ride my trike mostly around town and take something with two wheels if there is any distance involved.