Depends on how you define "generic". Moving from unlined housings to lined and/or from low end galvanized wires to die-drawn stainless will make noticeable differences.
But if you start with decent quality lined housings and stainless inners, additional improvements will not be as significant. You're also more likely to notice differences if the cable runs have a more or sharper curves.
Overall, I believe that the best value is found in the basic lined/SS cable kits. The money saved might fund earlier replacement as the housing liners wear.
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