I recently got a new bike (Hooray me!) and the saddle just sucked. I try not to switch out things (tires excepted) without giving them a chance, but this thing hurt from mile one. At about mile 9 or so, I changed the saddle position, and that got me through the 28 miles, but it was never comfortable, and moving it up shortened my cockpit too much.
I bought a new saddle. So far this one is much better. We'll see. Saddles confuse me about as much as bicycle geometry. I can't understand either.