I come from the GAP area - I usually take Bergen (Dean on the way back) to Smith. Smith turns in to Jay and deposits you at the bike ramp for the Manhattan Bridge (not a fan of the foot traffic that the BK Bridge can attract). From there, take Chrystie to Houston. Houston a couple blocks to Lafayette. 9th street over to 6th Ave and then up. The only stretch that doesn't have a bike lane is the couple blocks on Houston.