Been there, and it's not fun. Most of my stock saddles created massive shrinkage, and some left me with a completely numb wiener. It turned out that my seat bones are wider than normal, and I require a wider than usual seat. I moved to a wicked wide Brooks B68, and it has been a love story. I could get a woody while sitting on that baby.

As you can see, my butt is rather tiny looking. But butt size is no indication of seat bone width.