I think I see. Yow want to do something loke a kids tricycle or an old fashioned high wheeler.
Not with a conventional hub. The stresses on the pedals and cranks are too high, and the configuration is wrong. You'd need to remove the bearings from the hub. Mount it rigidly on a decently strong shaft, sort of like on bottom brackets, then use bearings similar to those on external BBs, except that the outer races of these bearings would be fitted to the blades of a fork.
There are lots of ways to design this, but you have to figure out a way to carry power from the cranks through a pair of bearings to a central area around which the wheel can be built. You might want to look at unicycles, and tricycles for ideas. The biggest part of design is to study what others have done before you, then advance it from there.
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