Just out of curiosity I looked at the route description:
"Riders who continue past Amanda experience a rigorous, rolling ride through the Hocking Hills of Southeastern Ohio. There is 5400 feet of net vertical gain during the 59-mile ride from Amanda to Athens."
5400 ft of elevation gain in the last 59 miles comes out to 91 ft / mile over that stretch. In my opinion 91 ft/mile is very hilly and strenuous, and personally as a borderline B / BB class rider I would be a bit intimidated by this ride, especially when combined with the 43 mile ride leading up to that stretch which is probably no cakewalk either. Unless you know you are good on hills and can handle similar terrain, I predict it is going to hurt a LOT. A ride like this also requires good technique when shifting - you have to shift at the right time to be efficient, keeping a high enough cadence to not strain your legs. Hopefully your bike has low enough gearing to allow you to use a reasonably high cadence.
Good luck if you try it.