As a closet economist I must ask the question: What is the incentive for buying domestically? We all have closet love affairs with Italian frames, Japanese parts, English leather saddles, etc. I've just never drank the "if it's from the USA, I'm a better American" koolaid. I would argue that trading globally translates to a strong world citizenship.
That said, Duluth Packs (USA, Whooho America Man!) make some fine cycling bags. I own 2 and I fully suspect they'll outlive me.