Just doing a little reading, there is a new test in the study stage that detects Engrailed-2 a protein found in the urine if men with prostate cancer, if they can work this into a commercial product, you go to the pharmacy, buy the kit, take it to your doctors office, open it up and pee on the stick, and then your doctor looks at it, and tells you your prostate in cancerous, then do the biopsy. One of the issues with PSA is that if there are false positives, there is also the possibility of a false negative, which could have much more dire consequences.