cyqlist

That's always my first preference, but it's not always possible or practical. There will be times when the tube has to be replaced, or the puncture can be much easier to find with the wheel off. I remember reading somewhere about a way to carry a spare tube in such a way that it can be installed without removing the wheel, but can't remember where it was and never tried it myself. Adjusting the shift cable never seemed like a big deal to me, just takes a few seconds, at least with the hubs I have used. I would not count on the adjustment staying the same when the wheel has been removed and reinstalled.